The Polish Mother and Child Cohort is multicentre prospective study on different exposures.
Prospective cohort study design enables identification of exposures that may influence pregnancy outcome and chil­dren’s health, verification of such exposures by biomarker measurements and notification of any changes in exposure levels.
The aim of the study is to evaluate the impact of exposure to different environmental factors during pregnancy and after birth on pregnancy outcome and children’s health. Specific research hypotheses refer to the role of heavy metals, exposure to phthalates, polycyclic aromatic hydrocar­bons (PAHs) and environmental tobacco smoke (ETS) in the aetiology of intrauterine growth retardation (IUGR), preterm delivery (PD) and the risk of respiratory diseases, allergy and poor mental and physical development. It is also intended to explain the role of oxidative stress and nutritional status of the pregnant women. The impact of occupational exposures and stressful situations on pregnancy outcome will be evaluated from question­naire data.

The results of the study will help to determine levels of child prenatal and postnatal exposure in several areas of Poland and their im­pact on course and outcome of pregnancy and children’s health and neurodevelopment.


Polish Mother and Child Cohort Study is supported by three projects:

1. The project entitled: "Epidemiology of reproductive hazards in Poland - multicentre, prospective cohort studies" founded by the National Center for Research and Development, Poland (grant no. PBZ-MEiN-/8/2//2006; contract no. K140/P01/2007/

2. The project entitled "Prenatal and postnatal exposure to tobacco smoke, PAHs and heavy metals and the risk of respiratory diseases, allergy and poor mental and physical development" supported by the grant PNRF-218-AI-1/07 from Norway through the Norwegian Financial Mechanism within the Polish-Norwegian Research Fund.

The Project is carried out in the cooperation with The Norwegian Institute of Public Health.

3. The project entitled "Phthalate exposure and birth outcome and child neurodevelopment" supported by the DEC-2011/01/B/NZ7/06462 grant from the National Science Centre.